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Thalassemia Transplant Treatment in India

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Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. It may be autologous (the patient’s own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin).

It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient’s immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT.

Hematopoietic stem cell transplantation remains a dangerous procedure with many possible complications, it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer to autoimmune diseases and hereditary skeletal dysplasias, notably malignant infantile osteopetrosis and mucopolysaccharidosis.

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Recommened Doctors for Treatment

  • Bone Marrow and Stem Cell, Autologous for Lymphomas - Bone MarrowLaparoscopic Surgery and Renal TransplantThalassemia Transplant Director, DM, MD, MBBS, 21 years of experience

Thalassemia is an inherited blood disorder that causes the body to make less haemoglobin or abnormal haemoglobin.

Stem Cell or Bone Marrow Transplant

Stem cell transplant, or bone marrow transplant, is a treatment performed to replace damaged stem cells with healthy ones. For a transplant, stem cells from a healthy donor are given through a drip into a vein. These cells then start to produce healthy red blood cells to replace the cells affected by thalassaemia.

A stem cell or bone marrow transplant involves five main stages.

These stages are:

  • Tests and examinations – to assess the general level of health.
  • Harvesting – the process of obtaining the stem cells to be used in the transplant, either from the patient or donor.
  • Conditioning – treatment to prepare the body for the transplant.
  • Transplanting the stem cells.
  • Recovery – Patient needs to stay in the hospital for at least a few weeks until the transplant starts to take effect.

Patient can leave the hospital between one and three months after the transplant.

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